As i often play games with two (live or on BGA/Yucata sites), even when a game is meant for larger count of players, i’ve decided to share a list of my best games meant for larger number of players which can be played with two. Most often i play with two because of a faster gameplay. Because when playing on the Internet it already takes very long as you take a turn or few per day. So this way you are not forgetting what you were going to do in the game, your turns come faster. Also, some games, in my opinion, have too much chaos and luck when playing with larger count of players.
I often play this game with three. But it is also much fun with two. There is still plenty of space for competition with a fewer count of players. Also, when you only have one opponent you can have some long-term strategies without fearing, that someone will grab the card you need or take the spot you want on a tower.
Same as with Firenze, this game is well enough with 3 players, but when you play with two there is a wider strategic space. Also the game lasts a bit longer and you manage to build more buildings, while when playing with three the game often ends unexpectedly.
The game is interesting enough with 3 players as well, because you can always have a better turn while two others fight with each other. But this game is very simple and fast, so in general i tend to want to play it with only two. Then it gives a feeling like you are playing chess or a similar game.